2. Anti-hypertensive Therapy Based on Pathophysiology
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چکیده
منابع مشابه
Practical combination therapy based on pathophysiology of type 2 diabetes
Type 2 diabetes is a complex, chronic, and progressive condition that often necessitates the use of multiple medications to achieve glycemic goals. Clinical guidelines generally recommend intensifying pharmacotherapy if glycemic goals are not achieved after 3 months of treatment. However, for many patients with type 2 diabetes, treatment intensification is delayed or does not occur. Initiating ...
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Unlike the majority of patients with uncomplicated hypertension in whom minimal renal damage develops in the absence of severe blood pressure (BP) elevations, patients with diabetic and nondiabetic chronic kidney disease (CKD) exhibit an increased vulnerability to even moderate BP elevations. Investigations in experimental animal models have revealed that this enhanced susceptibility is a conse...
متن کاملThe Pharmacogenomics of Anti-Hypertensive Therapy
Hypertension is a major public health problem, but measures to reduce blood pressure and thus cardiovascular risk are complicated by the high prevalence of treatment resistance, despite the availability of multiple drugs. Drug side-effects contribute considerably to suboptimal blood pressure control. Clinicians must often rely on empirical methods to match patients with effective drug treatment...
متن کاملEmerging concept of anti-hypertensive therapy based on ambulatory blood pressure profile in chronic kidney disease.
Presently hypertensive patients with chronic kidney disease (CKD) particularly diabetic nephropathy are increasing in number, and cardiovascular and renal complications are the most common cause of death in these patients. The control of blood pressure (BP) is an important issue in cardiovascular and renal protection in hypertensive patients with CKD. Although hypertension is usually diagnosed ...
متن کاملIntravenous therapy for hypertensive emergencies, part 2.
PURPOSE Intravenous antihypertensive agents for the treatment of hypertensive emergencies are reviewed. SUMMARY An estimated 500,000 people in the United States experience a hypertensive crisis annually. Hypertensive emergency is associated with significant morbidity in the form of end-organ damage. Rapid controlled reduction of blood pressure (BP) may be necessary to prevent or minimize end-...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2017
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.106.516